About Us

CISCAREX

CISCAREX UG was founded on 4 April 2019 in Berlin.

CISCAREX UG is actively involved in current nutrition and health research.

CISCAREX UG holds the exclusive licences for the intellectual property / patents in the EU, USA, China, Australia, Canada and Japan for the synthesis and use of vitamin A5.

CISCAREX UG owns the rights for the trade names / trademarks MIN A5? and A5?.

CISCAREX UG is an experienced team with expertise in sales, marketing and scientific research.

Our mission

For more than 20 years, we have been specifically looking for substances in food that are beneficial for health in general and mental health in particular.

Over the years, we have realised that vitamins are important micronutrients in a balanced and healthy diet. But there are still some pieces missing in this complicated puzzle to explain the effect of a balanced diet on the health of the human organism.

Only by combining the expertise of our multinational team has it been possible, after 20 years of intensive scientific research, to discover an important new substance in the human food chain:

Vitamin A5, the first newly discovered vitamin in over 80 years.

Vitamin A5 is a very important component of a balanced and healthy diet.

Scientific publications from the CISCAREX team

  • The postulation of a new vitamin, vitamin A5
    Rühl R., Krezel W., de Lera A.R. (2018)
    "9-cis-13,14-dihydro-retinoic acid; a new endogenous mammalian RXR ligand and the active ligand of a potential new vitamin A category; Vitamin A5"
    Nutr. Rev. 76(12), 929-941.
  • The identification of a new vitamin, vitamin A5
    Krezel W., Rivas A., Szklenar M., Ciancia M., Alvarez R., de Lera A.R., Rühl R. (2021)
    "Vitamin A5/X, a new food to lipid hormone concept for a nutritional ligand for control of RXR-mediated signalling"
    NUTRIENTS 13(3), 925.
  • Suggested nutritional guidelines for vitamin A5
    Bohn T., Hellmann-Regen J., de Lera A.R., Böhm V., Rühl R. (2023)
    "Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X"
    Nutr. Met. 20; 34
  • Proposals for a new improved dietary recommendation for vitamins with a focus on vitamin A5
    Banati D and Rühl R.
    "Analysis of the current vitamin A terminology and dietary regulations from vitamin A1 to vitamin A5"
    Int. J. Vitam. Nutr. Res. 94 (5-6), 326-333
  • Definition of vitamin A5 deficiency
    Banati D., Hellman-Regen J., Mack I., Eggersdorfer M., Rohn S., Dulinska-Litewka J., Krezel W. and Rühl R.
    "Defining a vitamin A5/X deficiency - vitamin A5/X as a critical dietary factor for mental health"
    Int. J. Vitam. Nutr. Res. 94, (5-6), 443-475.

Patents

"Precursor compounds for providing retinoids of the vitamin A5 pathway and uses therof"

PCT / HU2017 / 091937 - WO2018091937
Inventors: R. Rühl / W. Krezel / A.R. de Lera